British researchers found that inflammation -- activation of the body's innate immune system -- is associated with a small but statistically significant later risk of dementia. They reported their findings July 19 in the journal PLOS ONE.
The U.S. National Cancer Institute defines systemic inflammation as aserious condition involving inflammation throughout the whole body.This may be caused by an infection, trauma, surgery, ischemia (lack of blood supply to a part of the body), or certain conditions, such as an autoimmune disorder or pancreatitis.
Data from the U.K. Biobank on a half-million people showed the association between dementia and systemic inflammation, according to the authors.
"This association, of course, does not mean causality, therefore, further research is needed to understand and evaluate the potential mechanism," said study author Krisztina Mekli.
Full text: Health Today
Proton pump inhibitors were strongly linked with serious infection risk in the digestive tract; lower respiratory tract; kidney or urinary tract; ear, nose and throat sphere; and nervous system among infants and young children, according to a study published in JAMA Pediatrics. Researchers followed more than 1 million children over four years and found PPIs were tied to a 34% increase in infections resulting in hospitalization, and the risk of viral infections was 30% higher and bacterial infections was 56% in children who took PPIs, compared with those who didn't. PPI use should be limited in infants and children, study suggests.
Full text: MedPage Today
Depression and sleep are intertwined. Not sleeping enough can exacerbate depressive symptoms, making it difficult to cope with daily life. Better sleep can be achieved through an established bedtime routine, time spent outdoors, regular physical activity, strategically timed rest during the day, limits on alcohol consumption and cognitive behavioral therapy with a mental health clinician.
Full text: CNET
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